All kick-off times in GMT.
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- Fri, Feb 1, 2013
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| FT | Caen | 1 - 0 | Nimes |
| FT | FC Istres | 0 - 0 | Angers |
| FT | Guingamp | 4 - 3 | Niort |
| FT | Le Havre AC | 3 - 0 | Dijon FCO |
| FT | Lens | 2 - 0 | Ajaccio GFCO |
| FT | Sedan | 1 - 1 | Clermont Foot |
| FT | Stade Laval | 4 - 5 | AJ Auxerre |
| FT | Tours | 3 - 1 | Chateauroux |
| FT | Akhisar Belediye | 1 - 2 | Kayserispor |
| FT | Besiktas | 2 - 2 | Karabukspor |